Causes of Hair Loss and the Current Treatments

Causes of Hair Loss and the Current Treatments

 

Dr.Hamid HoseiniAuthor: Dr. Hamid Hosseini, MD, MBioMed & PHD

 

(CEO & Founder of Hamita Biotech who discovered the unique formula of Dr. Hamid Hair Regrowth Products. A Clinician, Researcher & Immunologist who specialised in hair physiology & aesthetic medicine; Melbourne, Australia).

Causes of Hair Loss and the Current Treatments 

Hair loss is a common concern affecting both men and women. Several factors contribute to this issue, including an imbalance in the hair growth cycle, the formation of androgens or DHT (dihydrotestosterone), and environmental influences. Hereditary factors, hormonal imbalances, stress, illnesses, medications, chemotherapy, radiation therapy, and natural aging are among the many culprits of hair loss or alopecia (1,2,3).

Throughout history, people have been striving to find compositions and methods to stimulate hair growth and prevent or minimize hair loss in order to maintain or regain their hair. Pharmaceutical, nutraceutical, and cosmetic industries have been researching and developing compositions in the attempt of promoting hair growth or preventing hair loss for many years (1,3). Unfortunately, despite the fact that more and more people suffer from hair loss, existing hair loss treatments are not always effective or do not provide long-term solutions (4). Therefore, people go under invasive and costly hair transplants or cannot perform hair transplants due to insufficient hair storage as a bank (5).

Numerous factors impact hair growth, encompassing environmental conditions like temperature and sunlight, dietary factors, disease presence or absence, hormonal fluctuations, pregnancy, radiation exposure, and more (6,7).

 

Causes of Hair Loss and the Current Treatments-factors

 

Hair loss stems from two primary causes

Internal factorsInternal factors

Internal factors involve increased 5-alpha reductase activity, elevating sebum production by converting testosterone into dihydrotestosterone (DHT).

external factorsexternal factors

External environmental factors may lead to hair bulb malnutrition due to restricted blood flow caused by constricted blood vessels and scalp dryness. The most prevalent form of hair loss, androgenetic alopecia, affects 80% of men and 50% of women (3,8).

 

Hair loss patterns

 

Typically, hair loss initiates with receding hairlines at the temples, generalized thinning at the vertex, and total hair loss at the vertex's center. The bald patch at the vertex eventually merges with the receding frontal hairline, leaving only a hair "island" at the frontal scalp. This island gradually vanishes, leaving hair solely in the parietal and occipital regions. Other less common patterns include faster hair loss at the vertex compared to the frontal area, frontal hairline loss preceding vertex balding, and a Ludwig-type pattern with the preservation of the frontal hairline (3,9).

The Hamilton- Norwood scale is employed to assess the extent and severity of androgenetic alopecia in men, while the Ludwig scale is preferred for women. Both men and women exhibit higher levels of androgen receptors and alpha-reductase type I and II activities in the frontal scalp area than in the occipital region, which has higher aromatase levels. This indicates that male androgenetic alopecia is androgen-dependent, but the role of androgen signalling in women remains uncertain (10,11,12,13).

 

Hair treatment

 

While various drugs and products are available for hair loss treatment, most address only one aspect of the problem and offer partial effectiveness. This gap in sustainable, reliable, and efficient hair loss solutions led to the development of Dr. Hamid Hair Regrowth products.

Both surgical and non-surgical options exist to combat hair loss. Non-surgical approaches encompass pharmaceutical and nutraceutical topical and/or oral treatments designed to stimulate hair regrowth and prevent further loss. For instance, topical minoxidil, often known as ROGAINE, encourages hair growth and slows hair loss by stimulating hair follicles when applied to the scalp. Finasteride, or PROPECIA, is an oral medication that treats androgenic alopecia by inhibiting DHT formation. However, pharmaceutical treatments may entail side effects such as low blood pressure, increased heart rate, weight gain due to water retention, scalp inflammation, genital deformities in male infants, impotence, decreased libido, hives or rash, and swelling (3,4,9). 

 

suggestion of Dr.hamid's products to treat Hair loss

 

Despite advancements in previous treatments, there was a pressing need for innovative solutions. Dr.Hamid Hair Regrowth products were developed using carefully composed natural ingredients to rejuvenate skin, promote hair growth/regrowth, and prevent/minimize hair loss. These products offer a comprehensive and effective approach to address various facets of the issue in a single package.

ReferenceReferences
  1. DiMarco G, McMichael A. Hair Loss Myths. J Drugs Dermatol. 2017 Jul 1;16(7):690–4.
  2. Alessandrini A, Bruni F, Piraccini BM, Starace M. Common causes of hair loss - clinical manifestations, trichoscopy and therapy. J Eur Acad Dermatol Venereol. 2021 Mar;35(3):629–40.
  3. Phillips TG, Slomiany WP, Allison R. Hair Loss: Common Causes and Treatment. Am Fam Physician. 2017 Sep 15;96(6):371–8.
  4. Nestor MS, Ablon G, Gade A, Han H, Fischer DL. Treatment options for androgenetic alopecia: Efficacy, side effects, compliance, financial considerations, and ethics. J Cosmet Dermatol. 2021 Dec;20(12):3759–81.
  5. Hadshiew IM, Foitzik K, Arck PC, Paus R. Burden of hair loss: stress and the underestimated psychosocial impact of telogen effluvium and androgenetic alopecia. J Invest Dermatol. 2004 Sep;123(3):455–7.
  6. Park AM, Khan S, Rawnsley J. Hair Biology: Growth and Pigmentation. Facial Plast Surg Clin North Am. 2018 Nov;26(4):415–24.
  7. Thom E. Stress and the Hair Growth Cycle: Cortisol-Induced Hair Growth Disruption. J Drugs Dermatol. 2016 Aug 1;15(8):1001–4.
  8. Buffoli B, Rinaldi F, Labanca M, Sorbellini E, Trink A, Guanziroli E, et al. The human hair: from anatomy to physiology. Int J Dermatol. 2014 Mar;53(3):331–41.
  9. York K, Meah N, Bhoyrul B, Sinclair R. A review of the treatment of male pattern hair loss. Expert Opin Pharmacother. 2020 Apr;21(5):603–12.
  10. Bertoli MJ, Sadoughifar R, Schwartz RA, Lotti TM, Janniger CK. Female pattern hair loss: A comprehensive review. Dermatol Ther. 2020 Nov;33(6):e14055.
  11. Starace M, Orlando G, Alessandrini A, Piraccini BM. Female Androgenetic Alopecia: An Update on Diagnosis and Management. Am J Clin Dermatol. 2020 Feb;21(1):69–84.
  12. Shrivastava SB. Diffuse hair loss in an adult female: approach to diagnosis and management. Indian J Dermatol Venereol Leprol. 2009;75(1):20–7; quiz 27–8.
  13. Gupta M, Mysore V. Classifications of Patterned Hair Loss: A Review. J Cutan Aesthet Surg. 2016;9(1):3–12.
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